Dominique Vantomme first studied classical piano, then switched to jazz at the age of 20. He took lessons from pianists Mike Del Ferro and Marc Matthys at the Royal Music Conservatory in Ghent and attended workshops given by Mark Levine and Rob Madna.

In 1996, he attended another workshop with Andy Laverne and David Baker at the University of Louisville, Kentucky (USA).

From '96 to '98 he had electric jazz bands 'Fuzzlite' and 'Jazziz' together with one of his best friends and musicians Tom Mahieu. In 98, he studied in New York with US pianist Kenny Werner. In 99, he received a Prize at the Europ' Jazz Contest in Hoeilaart (B) and was laureate of the Torneo Internationale Musicale (Jazz) Rome.

Dominique Vantomme leads his own bands and works as a freelance pianist and keyboard player for various bands, including work in recording studios for jazz and folk/world. He has played with Toots Thielemans (B), Judy Niemack (USA), Theresa Malenfant (Can), Laurent Maur (Fr), George Kilby Jr. (USA), Aidan Burk (Irl), David Ray Hadley (USA), Jakob Rostoll (Dan), Louisiana Red (USA), Hans Van Oost (B), Rietta Austin (NZ), John O'Leary (UK), Daithi Rua (Irl), Pascal Schumacher (Lux), Rufus Stone (UK), Jules Fothergill (UK), Coco Jr. (B), Laïs (B), Cosmo St.-Clair (USA), Plane Vanilla (B), Boo Boo Davis (USA), Ana Popovic (Yo), Junior Jazz (B), Roland Van Campenhout (B), Viktor Lazlo (B), An Pierlé (B), PJDS (B), Ronny Mosuse (B), etc.